Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genomic signatures of germline gene expression.

Genome research - 1 Nov 2010

McVicker Graham, Green Phil

Abstract excerpt

Transcribed regions in the human genome differ from adjacent intergenic regions in transposable element density, crossover rates, and asymmetric substitution and sequence composition patterns. We tested whether these differences reflect selection or are instead a byproduct of germline transcription, using publicly available gene expression data from a variety of germline and somatic tissues. Crossover rate shows...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Crossing Over, Genetic
Share to DNA Transposable Elements
Share to Fetus

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genome, Human

Share to Germ Cells

Share to Macaca

Share to Meiosis

Share to Organ Specificity

Source

Open in PubMed Open full text

Identifiers

PMID: 20686123
DOI: 10.1101/gr.106666.110
PMCID: PMC2963814

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genomic signatures of germline gene expression.PMID 20686123Read ↗

Sex differences in transcription-associated mutagenesis in the human germlineSemantic proximity Read ↗

Dependence of mutational asymmetry on gene-expression levels in the human genome.Semantic proximity Read ↗

Widespread transcriptional scanning in the testis modulates gene evolution ratesSemantic proximity Read ↗

How do mammalian transposons induce genetic variation? A conceptual framework: the age, structure, allele frequency, and genome context of transposable elements may define their wide-ranging biological impacts.Semantic proximity Read ↗

The transcript-centric mutations in human genomes.Semantic proximity Read ↗

Contrasting determinants of mutation rates in germline and somaSemantic proximity Read ↗

Transposable element-driven transcript diversification and its relevance to genetic disorders.Semantic proximity Read ↗

Interpreting mammalian evolutionary constraint at synonymous sites in light of the unwanted transcript hypothesisSemantic proximity Read ↗

Vertebrate Lineages Exhibit Diverse Patterns of Transposable Element Regulation and Expression across Tissues.Semantic proximity Read ↗

Transcription start sites experience a high influx of heritable variants fuelled by early developmentSemantic proximity Read ↗

Gene expression levels modulate germline mutation rates through the compound effects of transcription-coupled repair and damage.Semantic proximity Read ↗

Expression spectrum of TE-derived transcripts in human adult tissuesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.