Article
Active surveillance for scrapie by third eyelid biopsy and genetic susceptibility testing of flocks of sheep in Wyoming.
Clinical and diagnostic laboratory immunology - 1 Sept 2002
O'Rourke Katherine I, Duncan John V, Logan James R, Anderson Anne K, Norden Dianne K, Williams Elizabeth S, Combs Bret A, Stobart Robert H, Moss Gary E, Sutton Diane L
Abstract excerpt
Control of scrapie, an ovine transmissible spongiform encephalopathy or prion disorder, has been hampered by the lack of conventional antemortem diagnostic tests. Currently, scrapie is diagnosed by postmortem examination of the brain and lymphoid tissues for PrP(Sc), the protein marker for this group of disorders. For live, asymptomatic sheep, diagnosis using tonsil or third-eyelid lymphoid tissue biopsy and...
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