Article
Colorectal cancer and genetic polymorphism of DNA double-strand break repair gene XRCC4 in Taiwan.
Anticancer research - 1 Jul 2010
Bau Da-Tian, Yang Mei-Due, Tsou Yung-An, Lin Song-Shei, Wu Cheng-Nan, Hsieh Hao-Hsueh, Wang Rou-Fen, Tsai Chia-Wen, Chang Wen-Shin, Hsieh Hsiu-Min, Sun Shung-Shung, Tsai Ru-Yin
Abstract excerpt
The DNA repair gene X-ray repair complementing defective repair in Chinese hamster cells 4 (XRCC4) is thought to play a major role in the caretaking of the whole genome via double-strand break repair. However, the association of polymorphic variants of XRCC4 with colorectal cancer susceptibility has never been reported. In this hospital-based case-control study, the association of XRCC4 polymorphisms C-1622T...
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