Article
Lung cancer susceptibility and genetic polymorphism of DNA repair gene XRCC4 in Taiwan.
Cancer biomarkers : section A of Disease markers - 1 Jan 2009
Hsu Nan-Yung, Wang Hwei-Chung, Wang Chung-Hsing, Chang Chia-Lin, Chiu Chang-Fang, Lee Hong-Zin, Tsai Chia-Wen, Bau Da-Tian
Abstract excerpt
Non-homologous end-joining (NHEJ) system is a major route in repairing double strand breaks (DSBs), and is important in maintaining the genome stability. The gene XRCC4 is a central role of the NHEJ system, and it is critical in carcinogenesis. In order to reveal the association between XRCC4 and lung cancer, we recruited 164 lung cancer patients and 649 healthy controls from central Taiwan, investigated seven...
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