Article
A novel single nucleotide polymorphism in XRCC4 gene is associated with gastric cancer susceptibility in Taiwan.
Annals of surgical oncology - 1 Feb 2008
Chiu Chang-Fang, Wang Chung-Hsing, Wang Cheng-Li, Lin Cheng-Chieh, Hsu Nan-Yung, Weng Jing-Ru, Bau Da-Tian
Abstract excerpt
BACKGROUND: The DNA repair gene XRCC4, an important caretaker of the overall genome stability, is thought to play a major role in the human carcinogenesis. We investigate some novel and important polymorphic variants of XRCC4, at codon 247 (rs3734091), G-1394T (rs6869366), intron 3 (rs28360071), and intron 7 (rs28360317), of their associated with gastric cancer susceptibility. MATERIALS AND METHODS: In this...
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