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Article

XRCC1 R399Q polymorphism and colorectal cancer risk in the Chinese Han population: a meta-analysis.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Feb 2015

Qin Chang-Jiang, Xu Kai-Wu, Chen Zhi-Hui, Zhai Er-Tao, He Yu-Long, Song Xin-Ming

Abstract excerpt

X-ray repair cross-complementing group 1 (XRCC1) plays a key role in DNA repair, genetic instability, and tumorigenesis. The XRCC1 R399Q polymorphism has been reported in some studies to influence the risk of colorectal cancer (CRC), though this remains controversial. We performed a meta-analysis to determine the association of XRCC1 R399Q polymorphisms with CRC risk in the Chinese Han population. A literature...

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Identifiers

PMID: 25582318
DOI: 10.1007/s13277-015-3054-6

Genes

XRCC1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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