Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Susceptibility to Colorectal Cancer and Two Genetic Polymorphisms of XRCC4.

Pathology oncology research : POR - 1 Sept 2015

Emami Naghmeh, Saadat Iraj, Omidvari Shahpour

Abstract excerpt

The X-ray complementing group 4 (XRCC4, OMIM: 194363) plays a key role in non-homologous end-joining DNA repair pathway in mammalian cells. This pathway is believed to help maintain genomic stability. In the present study, it is hypothesized that genetic polymorphisms in the NHEJ repair XRCC4 gene may be associated with an increased risk in developing colorectal cancer (CRC). We genotyped two polymorphisms of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Case-Control Studies
Share to Colorectal Neoplasms
Share to DNA-Binding Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Follow-Up Studies

Share to Genetic Predisposition to Disease

Share to Polymerase Chain Reaction

Share to Polymorphism, Single Nucleotide

Share to Prognosis

Source

Identifiers

PMID: 25662981
DOI: 10.1007/s12253-015-9905-z

Genes

XRCC4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Susceptibility to Colorectal Cancer and Two Genetic Polymorphisms of XRCC4.PMID 25662981Read ↗

Colorectal cancer and genetic polymorphism of DNA double-strand break repair gene XRCC4 in Taiwan.Semantic proximity Read ↗

Association of XRCC1 Arg399Gln Polymorphism with Colorectal Cancer Risk: A HuGE Meta Analysis of 35 Studies.Semantic proximity Read ↗

A meta-analysis on XRCC1 and XRCC3 polymorphisms and colorectal cancer risk.Semantic proximity Read ↗

XRCC1 R399Q polymorphism and colorectal cancer risk in the Chinese Han population: a meta-analysis.Semantic proximity Read ↗

XRCC1 Arg399Gln polymorphism contributes to increased risk of colorectal cancer in Chinese population.Semantic proximity Read ↗

XRCC1 Arg399Gln Genetic Variant Increases Colorectal Cancer Susceptibility: A Comprehensive Meta-Analysis.Semantic proximity Read ↗

X-ray repair cross-complementing group 1 Arg399Gln gene polymorphism and susceptibility to colorectal cancer:a meta-analysis.Semantic proximity Read ↗

XRCC1 polymorphisms and risk of colorectal cancer: a meta-analysis.Semantic proximity Read ↗

Association between XRCC1 and XRCC3 polymorphisms and colorectal cancer risk: a meta-analysis of 23 case-control studies.Semantic proximity Read ↗

X-ray cross-complementing groups 1 rs1799782 C>T polymorphisms and colorectal cancer susceptibility: A meta-analysis based on Chinese Han population.Semantic proximity Read ↗

Association between the XRCC3 Thr241Met polymorphism and risk of colorectal cancer: a meta analysis of 5,193 cases and 6,645 controls.Semantic proximity Read ↗

Association between X-ray repair cross-complementing group 1 Arg194Trp polymorphism and colorectal cancer risk.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.