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Article

Chemokine receptor 5 (CCR5) delta 32 polymorphism in lupus nephritis: a large case-control study and meta-analysis.

Autoimmunity - 1 Sept 2014

Cheng Fa-Juan, Zhou Xu-Jie, Zhao Yan-Feng, Zhao Ming-Hui, Zhang Hong

Abstract excerpt

OBJECTIVES: Recent animal experiments showed that CCR5-deficient lupus mice (CCR5(-/-)) were closely associated with aggravated lupus nephritis. CCR5 Δ32 variation, a nonsynonymous mutation of CCR5, resulted in altered CCR5 function. However, the CCR5 Δ32 mutation in human lupus nephritis has been rarely reported in the literature. METHODS: A large case-control study that included 2010 samples from a Chinese...

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Source

Identifiers

PMID: 24720467
DOI: 10.3109/08916934.2014.906581

Genes

CCR5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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