Article
Differential CCR5Delta32 allelic frequencies in juvenile idiopathic arthritis subtypes: evidence for different regulatory roles of CCR5 in rheumatological diseases.
Scandinavian journal of rheumatology - 1 Jan 2000
Scheibel I, Veit T, Neves A G, Souza L, Prezzi S, Machado S, Kohem C, Icarelli M, Xavier R, Brenol J C, Chies J A B
Abstract excerpt
BACKGROUND: Juvenile idiopathic arthritis (JIA) is the most common chronic rheumatic disease of childhood and is characterized by persistent arthritis for at least 6 weeks. Its aetiopathogenesis is unknown but there is strong evidence that there is a substantial genetic component. Chemokine receptors genes are among the candidate genes for association with arthritis and other inflammatory diseases. The CC...
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