Article
Modelling spatially regulated beta-catenin dynamics and invasion in intestinal crypts.
Biophysical journal - 4 Aug 2010
Murray Philip J, Kang Jun-Won, Mirams Gary R, Shin Sung-Young, Byrne Helen M, Maini Philip K, Cho Kwang-Hyun
Abstract excerpt
Experimental data (e.g., genetic lineage and cell population studies) on intestinal crypts reveal that regulatory features of crypt behavior, such as control via morphogen gradients, are remarkably well conserved among numerous organisms (e.g., from mouse and rat to human) and throughout the diff...
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