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Article

Whole-embryo modeling of early segmentation in Drosophila identifies robust and fragile expression domains.

Biophysical journal - 20 Jul 2011

Bieler Jonathan, Pozzorini Christian, Naef Felix

Abstract excerpt

Segmentation of the Drosophila melanogaster embryo results from the dynamic establishment of spatial mRNA and protein patterns. Here, we exploit recent temporal mRNA and protein expression measurements on the full surface of the blastoderm to calibrate a dynamical model of the gap gene network on the entire embryo cortex. We model the early mRNA and protein dynamics of the gap genes hunchback, Kruppel, giant, and...

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Identifiers

PMID: 21767480
DOI: 10.1016/j.bpj.2011.05.060
PMCID: PMC3136765

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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