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Article

OCT1 polymorphism is associated with response and survival time in anti-Parkinsonian drug users.

Neurogenetics - 1 Feb 2011

Becker Matthijs L, Visser Loes E, van Schaik Ron H N, Hofman Albert, Uitterlinden André G, Stricker Bruno H Ch

Abstract excerpt

Substrates for the Organic Cation Transporter 1, encoded by the SLC22A1 gene, are metformin, amantadine, pramipexole, and, possibly, levodopa. Recently, we identified that the rs622342 A > C polymorphism is associated with the HbA1c lowering effect in metformin users. In the Rotterdam Study, we a...

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Identifiers

PMID: 20680652
DOI: 10.1007/s10048-010-0254-5
PMCID: PMC3029819

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20680652-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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