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Pharmacogenetic impact of SLC22A1 gene variant rs628031 (G/A) in newly diagnosed Indian type 2 diabetes patients undergoing metformin monotherapy.

Pharmacogenetics and genomics - 1 Apr 2023

Singh Shalini, Shukla Ashwin Kumar, Usman Kauser, Banerjee Monisha

Abstract excerpt

OBJECTIVES: Type 2 diabetes (T2D) imposes an enormous burden all over the world in both developed and developing countries. Inter-individual differences are attributed to polymorphisms in candidate genes resulting in altered absorption, transportation, distribution, and metabolism of oral antidiabetic drugs (OADs). Hence, the present study was undertaken to evaluate the pharmacogenetic impact of SLC22A1 gene...

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PMID: 36853844
DOI: 10.1097/FPC.0000000000000493

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