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Article

Prediction of metabolic fluxes by incorporating genomic context and flux-converging pattern analyses.

Proceedings of the National Academy of Sciences of the United States of America - 17 Aug 2010

Park Jong Myoung, Kim Tae Yong, Lee Sang Yup

Abstract excerpt

Flux balance analysis (FBA) of a genome-scale metabolic model allows calculation of intracellular fluxes by optimizing an objective function, such as maximization of cell growth, under given constraints, and has found numerous applications in the field of systems biology and biotechnology. Due to the underdetermined nature of the system, however, it has limitations such as inaccurate prediction of fluxes and...

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Identifiers

PMID: 20679215
DOI: 10.1073/pnas.1003740107
PMCID: PMC2930451

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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