Article
Genetic modification of flux for flux prediction of mutants.
Bioinformatics (Oxford, England) - 1 Jul 2009
Zhao Quanyu, Kurata Hiroyuki
Abstract excerpt
MOTIVATION: Gene deletion and overexpression are critical technologies for designing or improving the metabolic flux distribution of microbes. Some algorithms including flux balance analysis (FBA) and minimization of metabolic adjustment (MOMA) predict a flux distribution from a stoichiometric matrix in the mutants in which some metabolic genes are deleted or non-functional, but there are few algorithms that...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
