Article
Analysis on relationship between extreme pathways and correlated reaction sets.
BMC bioinformatics - 30 Jan 2009
Xi Yanping, Chen Yi-Ping Phoebe, Cao Ming, Wang Weirong, Wang Fei
Abstract excerpt
BACKGROUND: Constraint-based modeling of reconstructed genome-scale metabolic networks has been successfully applied on several microorganisms. In constraint-based modeling, in order to characterize all allowable phenotypes, network-based pathways, such as extreme pathways and elementary flux modes, are defined. However, as the scale of metabolic network rises, the number of extreme pathways and elementary flux...
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