Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Comparison of estrogens and estrogen metabolites in human breast tissue and urine.

Reproductive biology and endocrinology : RB&E - 2 Aug 2010

Taioli Emanuela, Im Annie, Xu Xia, Veenstra Timothy D, Ahrendt Gretchen, Garte Seymour

Abstract excerpt

BACKGROUND: An important aspect of the link between estrogen and breast cancer is whether urinary estrogen levels are representative of the intra-tissue levels of bioavailable estrogens. METHODS: This study compares 15 estrogen and estrogen metabolite levels in breast tissue and urine of 9 women with primary breast cancer using a quantitative liquid chromatography-mass spectrometry method. RESULTS: The average...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Breast
Share to Carcinoma, Ductal, Breast

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cytochrome P-450 CYP1B1

Share to Estradiol

Share to Estrogens

Share to Leucine

Share to Metabolic Networks and Pathways

Share to Metabolome

Source

Open in PubMed Open full text

Identifiers

PMID: 20678202
DOI: 10.1186/1477-7827-8-93
PMCID: PMC2922211

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Comparison of estrogens and estrogen metabolites in human breast tissue and urine.PMID 20678202Read ↗

The ratio of the estradiol metabolites 2-hydroxyestrone (2-OHE1) and 16α-hydroxyestrone (16-OHE1) may predict breast cancer risk in postmenopausal but not in premenopausal women: two case-control studies.Semantic proximity Read ↗

4-Hydroxyestradiol Promotes Breast Carcinogenesis via Androgen Receptor: Evidence from Urinary Metabolite Profiling and Functional StudiesSemantic proximity Read ↗

Urinary 2-hydroxyestrone/16alpha-hydroxyestrone ratio and family history of breast cancer in premenopausal women.Semantic proximity Read ↗

Genetic polymorphisms, the metabolism of estrogens and breast cancer: a review.Semantic proximity Read ↗

Excretion of estrogens, catecholestrogens and phytoestrogens in carriers of BRCA1 gene mutations: effects of metformin.Semantic proximity Read ↗

Circulating estrogens and estrogens within the breast among postmenopausal BRCA1/2 mutation carriers.Semantic proximity Read ↗

Breast cancer: a candidate gene approach across the estrogen metabolic pathway.Semantic proximity Read ↗

Association of genetic polymorphisms with serum estrogens measured multiple times during a 2-year period in premenopausal women.Semantic proximity Read ↗

CYP3A7*1C allele is associated with reduced levels of 2-hydroxylation pathway oestrogen metabolites.Semantic proximity Read ↗

Molecular epidemiology of breast cancer: genetic variation in steroid hormone metabolism.Semantic proximity Read ↗

SLCO1B1 polymorphisms and plasma estrone conjugates in postmenopausal women with ER+ breast cancer: genome-wide association studies of the estrone pathway.Semantic proximity Read ↗

Estrogen hydroxylation--the good and the bad.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.