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Article

Circulating estrogens and estrogens within the breast among postmenopausal BRCA1/2 mutation carriers.

Breast cancer research and treatment - 1 Feb 2014

Loud Jennifer T, Gierach Gretchen L, Veenstra Timothy D, Falk Roni T, Nichols Kathryn, Guttmann Allison, Xu Xia, Greene Mark H, Gail Mitchell H

Abstract excerpt

Accurately quantifying parent estrogens (PE) estrone (E1) and estradiol (E2) and their metabolites (EM) within breast tissue and serum may permit detailed investigations of their contributions to breast carcinogenesis among BRCA1/2 mutation carriers. We conducted a study of PE/EM in serum, nipple aspirate fluid (NAF), and ductal lavage supernatant (DLS) among postmenopausal BRCA1/2 mutation carriers. PE/EM...

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Source

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Identifiers

PMID: 24442642
DOI: 10.1007/s10549-013-2821-6
PMCID: PMC3955055

Genes

BRCA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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