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Article

Unique microRNA profile in Dupuytren's contracture supports deregulation of β-catenin pathway.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Nov 2010

Mosakhani Neda, Guled Mohamed, Lahti Leo, Borze Ioana, Forsman Minna, Pääkkönen Virve, Ryhänen Jorma, Knuutila Sakari

Abstract excerpt

Dupuytren's contracture, a proliferative disease of unknown origin, is characterized by an abnormal fibroblast proliferation process. Evidence from numerous microRNA (miRNA) studies shows that miRNAs have a vital function in many biological processes, for instance, in cellular signaling networks, cell growth, tissue differentiation, and cell proliferation. Our aim was to characterize, to our knowledge for the...

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Source

Identifiers

PMID: 20676061
DOI: 10.1038/modpathol.2010.146

Genes

TGFB1
ZIC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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