Article
New insights into the role of mitochondrial dysfunction and protein aggregation in Parkinson's disease.
Biochimica et biophysica acta - 1 Nov 2010
Xie Weilin, Wan Oi Wan, Chung Kenny K K
Abstract excerpt
Parkinson's disease (PD) is a common neurodegenerative movement disorder that affects increasing number of elderly in the world population. The disease is caused by a selective degeneration of dopaminergic neurons in the substantia nigra pars compacta with the molecular mechanism underlying this neurodegeneration still not fully understood. However, various studies have shown that mitochondrial dysfunction and...
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