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Article

Cell Death Pathways in Parkinson's Disease: Role of Mitochondria

7 May 2009

Abstract excerpt

Parkinson's disease (PD) is a progressive neurodegenerative disease and is characterized pathologically by selective loss of nigrostriatal dopaminergic neurons and the formation of Lewy bodies. Although in the majority of cases the cause of PD is unknown, mitochondrial dysfunction, environmental toxins, oxidative stress, and abnormal protein accumulation may all be involved in disease pathogenesis. The discovery...

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PMID: 19422283
DOI: 10.1089/ars.2009.2624

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