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Article

Parkinson's disease.

Human molecular genetics - 15 Oct 2007

Thomas Bobby, Beal M Flint

Abstract excerpt

Parkinson's disease (PD) is a chronic progressive neurodegenerative movement disorder characterized by a profound and selective loss of nigrostriatal dopaminergic neurons. Clinical manifestations of this complex disease include motor impairments involving resting tremor, bradykinesia, postural instability, gait difficulty and rigidity. Current medications only provide symptomatic relief and fail to halt the death...

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PMID: 17911161
DOI: 10.1093/hmg/ddm159

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