Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

PARK Genes Link Mitochondrial Dysfunction and Alpha-Synuclein Pathology in Sporadic Parkinson’s Disease

6 Jul 2021

Abstract excerpt

Parkinson’s disease (PD) is an age-related neurodegenerative disorder affecting millions of people worldwide. The disease is characterized by the progressive loss of dopaminergic neurons and spread of Lewy pathology (α-synuclein aggregates) in the brain but the pathogenesis remains elusive. PD presents substantial clinical and genetic variability. Although its complex etiology and pathogenesis has hampered the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Parkinson's Disease Mechanisms and Treatments
Share to Alzheimer's disease research and treatments
Share to Neurological diseases and metabolism

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 34295884
DOI: 10.3389/fcell.2021.612476

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

PARK Genes Link Mitochondrial Dysfunction and Alpha-Synuclein Pathology in Sporadic Parkinson’s DiseasePMID 34295884Read ↗

Molecular insights into Parkinson's disease.Semantic proximity Read ↗

Genetics and Pathogenesis of Parkinson's Syndrome.Semantic proximity Read ↗

Mitochondrial Dysfunction in Parkinson’s Disease: New Mechanistic Insights and Therapeutic PerspectivesSemantic proximity Read ↗

Mitochondrial dysfunction in Parkinson’s diseaseSemantic proximity Read ↗

Genetic findings in Parkinson’s disease and translation into treatment: a leading role for mitochondria?Semantic proximity Read ↗

Advancements in Genetic and Biochemical Insights: Unraveling the Etiopathogenesis of Neurodegeneration in Parkinson's Disease.Semantic proximity Read ↗

Understanding the molecular causes of Parkinson's disease.Semantic proximity Read ↗

Mitochondrial Contribution to Parkinson's Disease PathogenesisSemantic proximity Read ↗

Updates on the Genetics of Parkinson's Disease: Clinical Implications and Future Treatment.Semantic proximity Read ↗

Mitochondria and Parkinson’s Disease: Clinical, Molecular, and Translational AspectsSemantic proximity Read ↗

Molecular basis of Parkinson's disease.Semantic proximity Read ↗

The genetics and neuropathology of Parkinson's disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.