Article
[Interference of homologous sequences on the SNP study of CYP2A13 gene].
Zhongguo fei ai za zhi = Chinese journal of lung cancer - 1 Feb 2010
Hua Feng, Wan Haisu, Mei Chaorong, Zheng Dejie, Sun Linlin, Chen Jun, Liu Hongyu, Zhou Qinghua
Abstract excerpt
BACKGROUND AND OBJECTIVE: It has been proven that cytochrome P450 enzyme 2A13 (CYP2A13) played an important role in the association between single nucleotide polymorphisms (SNP) and human diseases. Cytochrome P450 enzymes are a group of isoenzymes, whose sequence homology may interfere with the study for SNP. The aim of this study is to explore the interference on the SNP study of CYP2A13 caused by homologous...
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