Article
SCYPPred: a web-based predictor of SNPs for human cytochrome P450.
Protein and peptide letters - 1 Jan 2012
Li Li, Wei Dong-Qing, Wang Jing-Fang, Chou Kuo-Chen
Abstract excerpt
Human cytochrome P450(CYP 450) enzymes mediate over 60% of the phase I-dependent metabolism of clinical drugs. They are also known for the polymorphism functions that have significant impacts on the enzyme activities. In this study, a web-server called SCYPPred was developed for predicting human cytochrome P450 SNPs (Single Nucleotide Polymorphisms) based on the SVM flanking sequence method; SCYPPred can rapidly...
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