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Article

Hemochromatosis gene (HFE) mutations and cancer risk

28 Jan 2010

Abstract excerpt

The possible role of iron as a causative factor in cancer development has been debated for a long time, based on often-contrasting results obtained in animal models and on clinical studies that are frequently hampered by the inclusion of a limited number of subjects. The rationale that makes iron a potential carcinogen is based on the capability of this metal to induce oxidative stress by catalyzing hydroxyl...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 20373367
DOI: 10.1002/hep.23541

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