Meiosis initiation in the human ovary requires intrinsic retinoic acid synthesis

Abstract excerpt

BACKGROUND: The initiation of meiosis is crucial to fertility. While extensive studies in rodents have enhanced our understanding of this process, studies in human fetal ovary are lacking. METHODS: We used RT-PCR and immunohistochemistry to investigate expression of meiotic factors in human fetal ovaries from 6 to 15 weeks post fertilization (wpf) and developed an organ culture model to study the initiation of...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Ovarian cancer diagnosis and treatment
• Share to Ovarian function and disorders
• Share to Reproductive Biology and Fertility