Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Analysis of meiosis regulators in human gonads: a sexually dimorphic spatio-temporal expression pattern suggests involvement of DMRT1 in meiotic entry

16 Aug 2012

Abstract excerpt

The mitosis-meiosis switch is a key event in the differentiation of germ cells. In humans, meiosis is initiated in fetal ovaries, whereas in testes meiotic entry is inhibited until puberty. The purpose of this study was to examine the expression pattern of meiosis regulators in human gonads and to investigate a possible role of DMRT1 in the regulation of meiotic entry. The expression pattern of DMRT1, STRA8,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
Share to Reproductive Biology and Fertility

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Sperm and Testicular Function

Source

Identifiers

PMID: 22899867
DOI: 10.1093/molehr/gas030

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Analysis of meiosis regulators in human gonads: a sexually dimorphic spatio-temporal expression pattern suggests involvement of DMRT1 in meiotic entryPMID 22899867Read ↗

Dysregulation of the mitosis–meiosis switch in testicular carcinoma in situSemantic proximity Read ↗

Regulation of meiotic entry and gonadal sex differentiation in the human: normal and disrupted signalingSemantic proximity Read ↗

Sex Determination in the Mammalian GermlineSemantic proximity Read ↗

Human foetal ovary shares meiotic preventing factors with the developing testisSemantic proximity Read ↗

DMRT proteins and coordination of mammalian spermatogenesisSemantic proximity Read ↗

Cell cycle regulation for meiosis in mammalian germ cellsSemantic proximity Read ↗

DMRT1: An Ancient Sexual Regulator Required for Human GonadogenesisSemantic proximity Read ↗

Unveiling the roles of Sertoli cells lineage differentiation in reproductive development and disorders: a reviewSemantic proximity Read ↗

Ontogenesis of Testis Development and Function in HumansSemantic proximity Read ↗

Characterization of the human fetal gonad and reproductive tract by single-cell transcriptomicsSemantic proximity Read ↗

The conserved sex regulator DMRT1 recruits SOX9 in sexual cell fate reprogrammingSemantic proximity Read ↗

Meiosis initiation in the human ovary requires intrinsic retinoic acid synthesisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.