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Regulation of germ cell meiosis in the fetal ovary

1 Jan 2012

Abstract excerpt

Fertility depends on correct regulation of meiosis, the special form of cell division that gives rise to haploid gametes. In female mammals, germ cells enter meiosis during fetal ovarian development, while germ cells in males avoid entering meiosis until puberty. Decades of research have shown that meiotic entry, and germ cell sex determination, are not initiated intrinsically within the germ cells. Instead,...

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PMID: 23417400
DOI: 10.1387/ijdb.120142pk

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