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Article

Human foetal ovary shares meiotic preventing factors with the developing testis

14 Dec 2016

Abstract excerpt

STUDY QUESTION: How can pre-meiotic germ cells persist in the human foetal ovary? SUMMARY ANSWER: Numerous oogonia escaping meiotic entry were retrieved throughout human ovarian development simultaneously with the expression of signalling pathways preventing meiosis, typically described in the rodent embryonic testis. WHAT IS KNOWN ALREADY: The transition from mitosis to meiosis is a key event in female germ...

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Share to Ovarian function and disorders
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PMID: 28073973
DOI: 10.1093/humrep/dew343

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