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Retinoic acid derived from the fetal ovary initiates meiosis in mouse germ cells

8 Aug 2012

Abstract excerpt

Meiotic initiation of germ cells at 13.5 dpc (days post-coitus) indicates female sex determination in mice. Recent studies reveal that mesonephroi-derived retinoic acid (RA) is the key signal for induction of meiosis. However, whether the mesonephroi is dispensable for meiosis is unclear and the role of the ovary in this meiotic process remains to be clarified. This study provides data that RA derived from fetal...

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PMID: 22886539
DOI: 10.1002/jcp.24172

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Retinoic acid derived from the fetal ovary initiates meiosis in mouse germ cellsPMID 22886539Read ↗

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