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Polymorphism of MTHFR C677T, serum vitamin levels and cognition in subjects with hyperhomocysteinemia in China.

Nutritional neuroscience - 1 Aug 2010

Cheng Dao-Mei, Jiang Yu-Gang, Huang Cheng-Yu, Kong Hai-Yan, Pang Wei, Yang Hong-Peng

Abstract excerpt

Relationships between hyperhomocysteinemia (HHE) and neurodegenerative diseases have been widely studied. However, the impact of serum total homocysteine (tHcy) levels on cognitive function has not been confirmed. C677T polymorphisms in the 5,10-methylenetetrahydrofolate reductase (MTHFR) gene have impacts on tHcy level; it is suspected to influence cognitive function, but only few investigations have assessed...

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Identifiers

PMID: 20670473
DOI: 10.1179/147683010X12611460764200

Genes

MTHFR

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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