Article
Diversity of the cagA gene of Helicobacter pylori strains from patients with gastroduodenal diseases in the Philippines.
FEMS immunology and medical microbiology - 1 Oct 2010
Cortes Maria Celeste C, Yamakawa Akiyo, Casingal Cristine R, Fajardo Lindsay Sydney N, Juan Ma Luisa G, De Guzman Blanquita B, Bondoc Edgardo M, Mahachai Varocha, Yamazaki Yukinao, Yoshida Masaru, Kutsumi Hiromu, Natividad Filipinas F, Azuma Takeshi
Abstract excerpt
Helicobacter pylori CagA protein is considered a major virulence factor associated with gastric cancer. There are two major types of CagA proteins: the Western and East Asian CagA. The East Asian CagA-positive H. pylori infection is more closely associated with gastric cancer. The prevalence of gastric cancer is quite low in the Philippines, although Philippine populations are considered to originate from an East...
Topics
- Adult
- Aged
- Antigens, Bacterial
- Bacterial Proteins
- Cluster Analysis
- DNA, Bacterial
- Female
- Genetic Variation
- Helicobacter Infections
- Helicobacter pylori