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Article

Helicobacter pylori with East Asian-type cagPAI genes is more virulent than strains with Western-type in some cagPAI genes.

Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] - 1 Jan 2000

Yuan Xiao-Yan, Yan Jin-Jun, Yang Ya-Chao, Wu Chun-Mei, Hu Yan, Geng Jian-Li

Abstract excerpt

The severity of Helicobacter pylori-related disease is correlated with the presence and integrity of a cag pathogenicity island (cagPAI). cagPAI genotype may have a modifying effect on the pathogenic potential of the infecting strain. After analyzing the sequences of cagPAI genes, some strains with the East Asian-type cagPAI genes were selected for further analysis to examine the association between the diversity...

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Identifiers

PMID: 28130020
DOI: 10.1016/j.bjm.2016.12.004
PMCID: PMC5470446

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