Article
Helicobacter pylori with East Asian-type cagPAI genes is more virulent than strains with Western-type in some cagPAI genes.
Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] - 1 Jan 2000
Yuan Xiao-Yan, Yan Jin-Jun, Yang Ya-Chao, Wu Chun-Mei, Hu Yan, Geng Jian-Li
Abstract excerpt
The severity of Helicobacter pylori-related disease is correlated with the presence and integrity of a cag pathogenicity island (cagPAI). cagPAI genotype may have a modifying effect on the pathogenic potential of the infecting strain. After analyzing the sequences of cagPAI genes, some strains wi...
Topics
- Cluster Analysis
- Gastric Mucosa
- Genomic Islands
- Genotype
- Helicobacter Infections
- Helicobacter pylori
- Histocytochemistry
- Humans
- Microscopy
- Phylogeny
- Virulence
- Virulence Factors
