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Article

Genetic diversity of Helicobacter pylori type IV secretion system cagI and cagN genes and their association with clinical diseases.

Scientific reports - 24 Jun 2023

Azizimoghaddam Yasaman, Kermanpour Sadaf, Mirzaei Nasrin, Houri Hamidreza, Nabavi-Rad Ali, Asadzadeh Aghdaei Hamid, Yadegar Abbas, Zali Mohammad Reza

Abstract excerpt

A number of cagPAI genes in the Helicobacter pylori genome are considered the most evolved genes under a diversifying selection and evolutionary pressure. Among them, cagI and cagN are described as a part of the two different-operon of cagPAI that are involved in the T4SS machinery, but the definite association of these factors with clinical manifestations is still unclear. A total of 70 H. pylori isolates were...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 37355714
DOI: 10.1038/s41598-023-37392-7
PMCID: PMC10290643

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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