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Linkage disequilibrium between the CYP2C19*17 allele and wildtype CYP2C8 and CYP2C9 alleles: identification of CYP2C haplotypes in healthy Nordic populations.

European journal of clinical pharmacology - 1 Dec 2010

Pedersen Rasmus S, Brasch-Andersen Charlotte, Sim Sarah C, Bergmann Troels K, Halling Jónrit, Petersen Maria S, Weihe Pál, Edvardsen Hege, Kristensen Vessela N, Brøsen Kim, Ingelman-Sundberg Magnus

Abstract excerpt

PURPOSE: To determine the distribution of clinically important CYP2C genotypes and allele frequencies in healthy Nordic populations with special focus on linkage disequilibrium. METHODS: A total of 896 healthy subjects from three Nordic populations (Danish, Faroese, and Norwegian) were genotyped for five frequent and clinically important CYP2C allelic variants: the defective CYP2C8*3, CYP2C9*2, CYP2C9*3, and...

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Aryl Hydrocarbon Hydroxylases
Cytochrome P-450 CYP2C19
Cytochrome P-450 CYP2C8
Cytochrome P-450 CYP2C9

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Linkage Disequilibrium

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PMID: 20665013
DOI: 10.1007/s00228-010-0864-8

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