Article
Somatic support cells restrict germline stem cell self-renewal and promote differentiation.
Nature - 12 Oct 2000
Kiger A A, White-Cooper H, Fuller M T
Abstract excerpt
Stem cells maintain populations of highly differentiated, short-lived cell-types, including blood, skin and sperm, throughout adult life. Understanding the mechanisms that regulate stem cell behaviour is crucial for realizing their potential in regenerative medicine. A fundamental characteristic...
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