Article
Can the HLA phenotype be used as a prognostic factor in breast carcinomas?
International journal of cancer. Supplement = Journal international du cancer. Supplement - 1 Jan 1991
Concha A, Cabrera T, Ruiz-Cabello F, Garrido F
Abstract excerpt
There is evidence indicating that change in the expression of HLA-ABC antigens can modulate the biological behavior and metastatic potential of certain neoplasms. We studied 15 samples of normal breast epithelium, 94 breast carcinomas and 24 benign and pre-malignant lesions of the mammary gland. All cases of normal breast epithelium and non-malignant lesions presented high levels of expression of class-I...
Topics
- Adult
- Aged
- Antibodies, Monoclonal
- Biomarkers, Tumor
- Breast
- Breast Diseases
- Breast Neoplasms
- Female
- HLA Antigens
- HLA-A Antigens
- HLA-B Antigens
