HLA class-II allele frequencies in Turkish breast cancer patients.

doi:10.1007/s12032-011-9873-4

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Article

HLA class-II allele frequencies in Turkish breast cancer patients.

Medical oncology (Northwood, London, England) - 1 Jun 2012

Gun Faik Deniz, Ozturk Ozlem Goruroglu, Polat Ayse, Polat Gurbuz

Abstract excerpt

Class-II human leukocyte antigens (HLA) present tumor antigenic peptides on the cell surface in order to be recognized by T lymphocytes. Thereby, these molecules can play an important role in the immune response to breast cancer tumor antigens. The aim of this study was to determine the relation between breast cancer and HLA class-II alleles in Turkey. The study groups consisted of 69 breast cancer patients and...

Topics

Alleles
Breast Neoplasms
Carcinoma, Ductal, Breast
Case-Control Studies
Female
Follow-Up Studies
Gene Frequency
Genotype
HLA-DQ beta-Chains
HLA-DRB1 Chains
Haplotypes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Humans

Immunoenzyme Techniques

Middle Aged

Neoplasm Recurrence, Local

Neoplasm Staging

Polymerase Chain Reaction

Postmenopause

Source

Open in PubMed

Identifiers

PMID: 21373933
DOI: 10.1007/s12032-011-9873-4

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