Article
HLA-DRB alleles are differentially expressed by tumor cells in breast carcinoma.
International journal of cancer - 10 Nov 2004
Oldford Sharon A, Robb J Desmond, Watson Peter H, Drover Sheila
Abstract excerpt
The biologic and prognostic significance of HLA-DR expression and T-cell infiltration in breast carcinoma are presently controversial. To test the hypothesis that these factors are influenced by particular HLA-DRB alleles, 52 breast tumor samples, composed of 26 DRB1*04 and 26 non-DRB1*04 tumors, were assessed using immunohistochemistry for expression of DR and its associated invariant chain (Ii) and for...
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