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Article

Analysis of transient hypermorphic activity of E(spl)D during R8 specification.

PloS one - 1 Jan 2017

Majot Adam T, Bidwai Ashok P

Abstract excerpt

Drosophila atonal (ato) is required for the specification of founding R8 photoreceptors during retinal development. ato is regulated via dual eye-specific enhancers; ato-3' is subject to initial induction whereas 5'-ato facilitates Notch-mediated autoregulation. Notch is further utilized to induce bHLH repressors of the E(spl) locus to restrict Ato from its initial broad expression to individual cells. Although...

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Identifiers

PMID: 29036187
DOI: 10.1371/journal.pone.0186439
PMCID: PMC5643056

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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