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Article

Pseudohyphal Regulation by the Transcription Factor Rfg1p in Candida albicans

24 Jul 2010

Abstract excerpt

The opportunistic human fungal pathogen Candida albicans is a major cause of nosocomial infections. One of the fundamental features of C. albicans pathogenesis is the yeast-to-hypha transition. Hypha formation is controlled positively by transcription factors such as Efg1p and Cph1p, which are required for hyphal growth, and negatively by Tup1p, Rfg1p, and Nrg1p. Previous work by our group has shown that...

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PMID: 20656914
DOI: 10.1128/ec.00088-10

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