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Article

Functional Dichotomy for a Hyphal Repressor in Candida albicans

8 Mar 2023

Abstract excerpt

Hypha formation is a central virulence trait of the fungal pathogen Candida albicans. Control of hypha formation has been studied in detail in the type strain but not in other diverse C. albicans clinical isolates. Here, we show that the hyphal repressor Nrg1 has an unexpected positive role in hypha formation and hypha-associated gene expression, as revealed by the sensitized P57055 strain background. Our...

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PMID: 36883818
DOI: 10.1128/mbio.00134-23

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