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The role of the C. albicans transcriptional repressor NRG1 during filamentation and disseminated candidiasis is strain dependent

20 Feb 2024

Abstract excerpt

ABSTRACT Candida albicans is one of the most common causes of superficial and invasive fungal diseases in humans. Its ability to cause disease is closely linked to its ability to undergo a morphological transition from budding yeast to filamentous forms (hyphae and pseudohyphae). The extent to which C. albicans strains isolated from patients undergo filamentation varies significantly. In addition, the...

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PMID: 38376205
DOI: 10.1128/msphere.00785-23

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