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Article

Candida albicans Tup1 is involved in farnesol-mediated inhibition of filamentous-growth induction.

Eukaryotic cell - 1 Jun 2008

Kebaara Bessie W, Langford Melanie L, Navarathna Dhammika H M L P, Dumitru Raluca, Nickerson Kenneth W, Atkin Audrey L

Abstract excerpt

Candida albicans is a dimorphic fungus that can interconvert between yeast and filamentous forms. Its ability to regulate morphogenesis is strongly correlated with virulence. Tup1, a transcriptional repressor, and the signaling molecule farnesol are both capable of negatively regulating the yeast to filamentous conversion. Based on this overlap in function, we tested the hypothesis that the cellular response to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 18424510
DOI: 10.1128/EC.00357-07
PMCID: PMC2446655

Genes

NRG1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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