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Article

Analysis of candidate genes on chromosome 20q12-13.1 reveals evidence for BMI mediated association of PREX1 with type 2 diabetes in European Americans.

Genomics - 1 Oct 2010

Lewis Joshua P, Palmer Nicholette D, Ellington Jennifer B, Divers Jasmin, Ng Maggie C Y, Lu Lingyi, Langefeld Carl D, Freedman Barry I, Bowden Donald W

Abstract excerpt

Chromosome 20q12-q13.1 has been linked to type 2 diabetes (T2D) in multiple populations. We examined the influence of genes in this region on T2D and BMI in two European American case-control populations. SNPs were genotyped in 300 diabetic patients and 310 controls. A subset of 72 SNPs were further genotyped in 470 cases and 442 controls. All genes examined showed evidence of association with T2D in the initial...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Chromosomes, Human, Pair 20

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Source

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Identifiers

PMID: 20650312
DOI: 10.1016/j.ygeno.2010.07.006
PMCID: PMC2977534

Genes

PREX1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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