Mapping genes influencing type 2 diabetes risk and BMI in Japanese subjects.

doi:10.2337/diabetes.52.1.209

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Article

Mapping genes influencing type 2 diabetes risk and BMI in Japanese subjects.

Diabetes - 1 Jan 2003

Iwasaki Naoko, Cox Nancy J, Wang Yan-Qing, Schwarz Peter E H, Bell Graeme I, Honda Masashi, Imura Mitsuo, Ogata Makiko, Saito Masayuki, Kamatani Naoyuki, Iwamoto Yasuhiko

Abstract excerpt

We have carried out an autosomal genome scan for genes contributing to the development of type 2 diabetes and affecting BMI in the Japanese population (164 families, 256 affected sib-pairs). We found 12 regions that showed nominally significant multipoint evidence of linkage with type 2 diabetes (i.e. logarithm of odds [LOD] score >0.59, P < 0.05): chromosome 1 29.9 cM; chromosome 2 169.6 and 236.8 cM; chromosome...

Topics

Asian People
Body Mass Index
Chromosome Mapping
Diabetes Mellitus, Type 2
Genetic Linkage
Genetic Predisposition to Disease
Humans
Japan

Source

Open in PubMed

Identifiers

PMID: 12502515
DOI: 10.2337/diabetes.52.1.209

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