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Article

Association study on chromosome 20q11.21-13.13 locus and its contribution to type 2 diabetes susceptibility in Japanese.

Human genetics - 1 Nov 2006

Tanahashi Toshihito, Osabe Dai, Nomura Kyoko, Shinohara Shuichi, Kato Hitoshi, Ichiishi Eiichiro, Nakamura Naoto, Yoshikawa Toshikazu, Takata Yoichiro, Miyamoto Tatsuro, Shiota Hiroshi, Keshavarz Parvaneh, Yamaguchi Yuka, Kunika Kiyoshi, Moritani Maki, Inoue Hiroshi, Itakura Mitsuo

Abstract excerpt

Several linkage studies have predicted that human chromosome 20q is closely related to type 2 diabetes, but there is no clear evidence that certain variant(s) or gene(s) have strong effects on the disease within this region. To examine disease susceptibility variant in Japanese, verified SNPs from the databases, with a minor allele frequency larger than 0.15, were selected at 10-kb intervals across a 19.31-Mb...

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PMID: 16955255
DOI: 10.1007/s00439-006-0231-0

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