Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Analysis of PBX1 as a candidate gene for type 2 diabetes mellitus in Pima Indians.

Biochimica et biophysica acta - 19 Mar 2001

Thameem F, Wolford J K, Bogardus C, Prochazka M

Abstract excerpt

The human proto-oncogene PBX1 codes for a homeodomain containing protein that modulates expression of several genes, including those contributing to regulation of insulin action and glucose metabolism. PBX1 is located on chromosome 1q22, a region linked with type 2 diabetes in Pima Indians, Cauca...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 3' Untranslated Regions
Share to DNA, Complementary
Share to Indians, North American

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Introns

Share to Proto-Oncogene Mas

Share to Proto-Oncogene Proteins

Share to Tissue Distribution

Share to United States

Source

Identifiers

PMID: 11267683
DOI: 10.1016/s0167-4781(01)00189-0

Genes

PBX1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-11267683-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Analysis of PBX1 as a candidate gene for type 2 diabetes mellitus in Pima Indians.PMID 11267683Read ↗

Evaluating the association of common PBX1 variants with type 2 diabetes.Semantic proximity Read ↗

Evaluation of sequence variants in the pre-B cell leukemia transcription factor 1 gene: a positional and functional candidate for type 2 diabetes and impaired insulin secretion.Semantic proximity Read ↗

Cloning, expression and genomic structure of human LMX1A, and variant screening in Pima Indians.Semantic proximity Read ↗

Molecular analysis of KCNJ10 on 1q as a candidate gene for Type 2 diabetes in Pima Indians.Semantic proximity Read ↗

Molecular characterization of the human PEA15 gene on 1q21-q22 and association with type 2 diabetes mellitus in Pima Indians.Semantic proximity Read ↗

An autosomal genomic scan for loci linked to prediabetic phenotypes in Pima Indians.Semantic proximity Read ↗

Linkage and association mapping of a chromosome 1q21-q24 type 2 diabetes susceptibility locus in northern European Caucasians.Semantic proximity Read ↗

The role of insulin receptor substrate-1 gene (IRS1) in type 2 diabetes in Pima Indians.Semantic proximity Read ↗

Variant screening of PRKAB2, a type 2 diabetes mellitus susceptibility candidate gene on 1q in Pima Indians.Semantic proximity Read ↗

Sequencing PDX1 (insulin promoter factor 1) in 1788 UK individuals found 5% had a low frequency coding variant, but these variants are not associated with Type 2 diabetes.Semantic proximity Read ↗

An autosomal genomic scan for loci linked to type II diabetes mellitus and body-mass index in Pima Indians.Semantic proximity Read ↗

Positional cloning of an obesity/diabetes susceptibility gene(s) on chromosome 11 in Pima Indians.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.