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Article

Association of GSTT1 and GSTM1 polymorphisms in South Indian Epilepsy Patients.

Indian journal of experimental biology - 1 Nov 2016

Prabha Turaga Surya, Kumaraswami Konda, Kutala Vijay Kumar

Abstract excerpt

Experimental studies suggest that oxidative stress is one of the contributing factors in the onset of epileptic seizures. Glutathione S-transferases (GSTs) are able to conjugate electrophilic compounds, and thus possess neuroprotective role by removing exogenous and endogenous oxidants, detoxifying therapeutic drugs, environmental toxins through conjugation with glutathione (GSH). Several studies from different...

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PMID: 30179425

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